Follow this list to make sure everything is up to date.
1) Make sure all programs/software required to run GTA is updated, and installed properly.
2) Make sure all programs/software required to run MTA is updated, and installed properly.
3) Experiment with compatibility settings for GTA & MTA (Google what works best for your issue)
4) If you installed any mods, try restoring your game to before the mods were installed, or reinstall your game.
5) You may have missing files for MTA/GTA, Try reinstalling MTA first, and if the problem persists then reinstall GTA.
6) Run MTA & GTA in administrator mode.
7) Try googling your problem.
8) (Optional, but recommended) Start up a single player game atleast once if you reinstalled GTA to ensure your game itself works.